Introduction

The Safe and Sustainable by Design approach requires an entire life cycle monitoring of the toxicity of chemicals. TOXBOX aspires to bring forth an instrument that will provide reliable toxicity data in relevant conditions for each chemical. The device will be based on a prototype developed in a H2020 project, PANBioRA, with a flexible microfluidic and instrument architecture to provide a plug and play testing platform to ease accessibility and interlaboratory validation. Progressive in silico models for long term effects will be iteratively developed.

TOXBOX expects to achieve:

• A flexible, all-in-one platform for comprehensive chemical toxicity testing.
• Advanced data integration and reliable computer models for better risk assessment.
• Reduced reliance on animal testing with alternative methods.
• Improved efficiency and cost-effectiveness in toxicology testing.
• Contributions to international safety regulations and standards.
• Support for sustainable product design from the start.
• Widespread adoption of new toxicology methods through collaborations and policy work.